A DNA-based nanogel (shown above) is broken down in cancer cells to release chemotherapy drugs. Credit: Adapted from Nano Letters 2020, Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells. Now, researchers reporting in ACS’ Nano Letters have designed DNA-based nanogels that only break down and release their chemotherapeutic contents within cancer cells, minimizing the impacts on normal ones and potentially eliminating painful and uncomfortable side effects.
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